Situated to the northeast of the Mulatas archipelago (Atlantic Ocean), the Comarca Kuna Yala (Kuna Yala indigenous reserve), previously known as the Comarca de San Blas, has a territorial extension of 3,206 km2 and extends from its limits with Colon Province to the borders of the Republic of Colombia.

The Comarca Kuna Yala is made up of the coastal strip defined by the San Blas mountain range and also includes more than 400 coral islands. Ringed by palm trees and white sand beaches which viewed from an airplane above seem to resemble a painting. In this tranquil area with its Caribbean blue waters and emerald green tones the tropical climate is in general refreshed by breezes. This group of islands is completely free of insects and snakes, an extraordinary achievement.

The majority of the 27,000 Kuna indigenous people inhabit only 52 of the islands in the closest coastal regions. Almost all the other islands are inhabited by just one person in charge of the care and protection of the coconut palm groves and their precious fruit, which, together with fish, form the principal source of their diet. Additionally, everything within the islands belong to the community and cannot be sold except for the coconut palms.

Kuna Yala is distributed among four corregimientos (counties): Nargana, Ailigandi, Tubuala, and Puerto Obaldía. Large canoes with sails called cayucos are still used today and for their size are capable of achieving high speeds. They continue to be the principal mode of transportation between islands and the main land.

The Kuna people are typically small in stature and uncomplicated in nature. Foreigners are charmed by the hospitality and friendliness of these people. As a result of efforts made by missionaries in modern times distinct religious groups have formed amongst the Kuna people.

This division has not promoted a community spirit which should unite such a small group of people with the same origins. In spite of this, many Kunas have maintained the beliefs of their ancestors with small modifications.

Kuna women are the repositories of tradition and culture. Their dress, jewelry, and beauty are a faithful reflection of the well-being of their family. They dress using the beautiful molas. Molas are considered one of the most sophisticated forms of artisanry in Latin America. They are made by women in thematically similar pairs similar and applied to the blouses they wear.

In complement to the molas the women also use brightly colored cloth tied at the waist in the style of a skirt and a red headscarf with yellow designs. Additionally they use adornments such as necklaces, rings, and bracelets of gold to complement their clothing. With special attention to their physical appearance Kuna women wrap their ankles and wrists with bracelets (called winis) made of brightly colored beads in order to maintain those parts of the body slim, which in their culture is a symbol of beauty.

The language heard is this beautiful Comarca is "Tule Galla," a native language, but many people also speak Spanish, the language used in schools and among religious groups.